Extended criteria (liver) donor (ECD)
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Definition of ECD donors
The ECD graft represents an organ with unfavourable characteristics
associated with suboptimal post-transplant outcomes that
fall into two main risk categories: poor graft function and potential
for disease transmission. Within the poor graft function category
it is possible to differentiate two groups, the DCDs and the
non-DCDs.
The Eurotransplant definition refers to the category of graft
dysfunction. According to this definition the following criteria
defines a liver donor marginal:
Donor age >65 years.
ICU stay with ventilation >7 days.
BMI >30.
Steatosis of the liver >40%.
Serum sodium >165 mmol/L.
Transaminases: ALT >105 U/L, AST >90 U/L.
Serum bilirubin >3 mg/dl.
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